Health & Life Sciences

Africa's Future in Clinical Research

Accelerating trials, equity, and innovation
ACRN is transforming how clinical research is done on the continent - building an African-led, globally connected network of high-quality trial sites, labs, and talent. Our model of scalable trial execution services is focused on breaking down barriers to deliver inclusive research where it matters the most.

The African Clinical Research Network (ACRN) is focused on strengthening Africa’s biomedical and life sciences industry. The network aims to enhance Africa’s ability to conduct clinical trials across all therapeutic areas ranging from cardiometabolic disease, oncology, hematology, neurology, nephrology to infectious diseases maternal & child health while fostering local scientific leadership and operational excellence. EIT, in partnership with Oracle, is strengthening ACRN’s digital infrastructure by delivering world-class clinical trial solutions and enabling the integration of AI to transform clinical research across Africa.

Program lead

Dr Tariro Makadzange

“ACRN was built to unlock the continent’s potential, accelerate lifesaving research and centre African leadership in science and innovation.”
The Situation

Global trials miss the mark without Africa

Africa is home to over 18% of the world’s population, but fewer than 3% of global clinical trials. Without inclusive research, the world risks developing treatments that do not reflect diverse populations.

7countries and 19 sites

ACRN has scaled rapidly across East, West, and Southern Africa.

65+staff and growing

Local experts in clinical operations, data, labs, and regulatory science.

5studies active or launching

Spanning maternal and child health, HIV and epidemiology studies.

The challenge

Bridging the divide in global health equity

For decades, Africa has been underrepresented in the global clinical trial landscape - not due to lack of need or talent, but due to fragmented infrastructure, funding silos, and inconsistent engagement from the pharmaceutical industry. ACRN exists to change that, creating a unified platform that links sites, builds local capacity, and derisks industry collaboration at scale.

Underrepresentation in research

Only 2–3% of global trials are conducted in Africa, limiting data on diverse populations.

Regulatory strengthening

Increasing number of African national regulatory authorities have progressed toward WHO ML3 benchmarks, with growing momentum for regulatory harmonization across the continent.

Health Systems Strengthening

Research integrating clinical research into care to broaden therapeutic areas of investigation and strengthen health systems.

Workforce development

Africa has talent - but training pipelines and research career pathways remain underfunded.

Community Engagement

Building trust through inclusive partnerships

Our approach

Africa-led, globally aligned

ACRN's model harnesses African leadership to deliver world class clinical trials. We align infrastructure, labs, data, and training under one umbrella - while advocating for regulatory harmonization and digital transformation.

AI-enabled epidemiology

Using mobile-first data tools and health foundation models to stratify patients into research-ready cohorts.

Site capacitation & services

Strengthening clinical trial sites with the tools, training and systems to succeed.

Regulatory coordination

Supporting multi-country submissions with national regulatory agencies, and sponsor engagement.

Workforce development

Partnering with industry to train, provide mentorship, and specialist roles that aim to retain African talent in research.

The team

A passionate, pan-African team of experts

Meet the team driving Africa’s research future:

Dr Tariro Makadzange

Dr. Tariro Makadzange is the CEO of ACRN, a medical social entrepreneur, infectious disease physician and expert in viral immunology. She is building a pan-African clinical research ecosystem with her team that aims to deliver globally competitive, high-quality trials while tackling Africa’s most pressing health challenges.

James Gregory

James Gregory is the Chief Operations Officer at ACRN. He has extensive experience in operational and financial management, specialising in transformative change within complex systems. He holds postgraduate qualifications in Accounting and Law, and has an MBA in Leadership and Quantitative Analysis.

Dr. Romina Mariano

Dr. Romina Mariano is the Chief of Staff at ACRN. She is an accomplished clinician and researcher specializing in clinical research, health policy, and strategy. She has led vaccine effectiveness studies across Africa, global disease prevention campaigns, and international health initiatives.

Wayne Janneker

Wayne Janneker is the Chief Technology Officer at ACRN. With over 20 years of experience in digital transformation within healthcare and corporate sectors, he has built high-performing IT operations and crafted strategic blueprints for Telemedicine, IoT, AI and Big Data solutions. Wayne has served as a technical advisor to South Africa's health departments and led complex IT programs for global health initiatives

Join our team

We’re gathering the greatest minds

EIT is growing rapidly and we are recruiting at pace. Thrive in a dynamic and fast-paced work environment, learning and growing every day alongside experts in science and technology.